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上気道感染症に対する定期的なゴールドキウイ摂取の影響

 

介入療法の手順に関係なく(キウイの次にバナナ、またはバナナの次にキウイ)、各治療またはウォッシュアウトの期間中に一つ以上のURTI症状を報告した被験者の割合は、臨床試験が進むとともに徐々に低下したため(データなし)、季節的な影響が生じていた可能性がある。それと同様に症状も、冬に比べて春に軽くなる傾向があった(データなし)。

 

 

 

URTIの発症期間(日数)に対する定期的なゴールドキウイ摂取の影響を評価した(表3)。参加者が28日以内の治療期間中に、咽頭痛や頭部うっ血を呈した場合、ゴールドキウイを摂取すると、バナナを摂取した時に比べて、この症状の期間が大幅に短縮された。バナナを摂取した参加者では咽頭痛が平均5.42日続いたが、キウイの場合では平均2.01日であった(P=0.024)。また、頭部うっ血の期間はバナナ群で平均4.69日、キウイ群で平均0.88日であった(P=0.029)。他の生理的症状に関しては、8つのうち4つの症状が改善する傾向にあったが、その程度は著しいものではなかった。機能的障害の期間はキウイ群でもそれほど短縮しなかった。

 

URTIの重症度に対する定期的なゴールドキウイ摂取の影響も評価した。重症度スコアの計算に関しては、症状を一日ずつ採点し、各治療期間の合計得点を求めた。定期的なキウイ摂取はバナナの場合と比べて、頭部うっ血の重症度を有意に低下させた(P=0.015、表4)。生理的症状は9つのうち5つ、さらに機能的症状は10のうち1つが改善する傾向にあったが、その程度は著しいものではなかった。

 

Influence of regular consumption of gold kiwifruit on
symptoms of upper respiratory tract infection
Irrespective of the order of intervention treatment (kiwifruit
and then banana, or banana and then kiwifruit), there was agradual decline in the proportion of subjects reporting one or
more symptoms of URTI during each treatment or washout
period as the trial progressed (data not shown), suggesting a
seasonal effect. Similarly, symptoms also tended to be less
severe in spring, compared with winter (data not shown).
The influence of regular consumption of gold kiwifruit on
the duration (number of days) of symptoms of URTI was
assessed (Table 3). When participants experienced a sore
throat or head congestion within the 28 d treatment period,
the duration of this symptom was significantly reduced
when gold kiwifruit was consumed compared with when
banana was consumed. A sore throat was present for an average
of 5·42 d when participants were consuming banana, but
this was significantly reduced to an average of 2·01 d when
kiwifruit was consumed (P¼0·024). Head congestion was
present for an average of 4·69 d when participants were
consuming banana, but this was significantly reduced to an
average of 0·88 d when kiwifruit was consumed (P¼0·029).
Of the remaining physiological domain symptoms, four of
eight tended to be reduced in duration but not significantly
so. Kiwifruit consumption did not significantly reduce the
duration of any of the functional symptoms.
The influence of regular consumption of gold kiwifruit on
the severity of symptoms of URTI was also assessed. The
severity scores were calculated as the sum of the daily symptom
ratings for each treatment period. Regular consumption of
kiwifruit compared with banana significantly reduced the
severity of head congestion (P¼0·015, Table 4). The severity
of a further five of nine physiological domain symptoms and
one of ten functional domain symptoms tended to be reduced
in severity but not significantly so.